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CAS

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156925-20-1

(R)-(-)-<4-(4-fluorobenzyl)-2-morpholinyl>methyl p-toluenesulfonate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 156925-20-1 Structure

  • Basic information

    1. Product Name: (R)-(-)-<4-(4-fluorobenzyl)-2-morpholinyl>methyl p-toluenesulfonate
    2. Synonyms:
    3. CAS NO:156925-20-1
    4. Molecular Formula:
    5. Molecular Weight: 379.452
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 156925-20-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-(-)-<4-(4-fluorobenzyl)-2-morpholinyl>methyl p-toluenesulfonate(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-(-)-<4-(4-fluorobenzyl)-2-morpholinyl>methyl p-toluenesulfonate(156925-20-1)
    11. EPA Substance Registry System: (R)-(-)-<4-(4-fluorobenzyl)-2-morpholinyl>methyl p-toluenesulfonate(156925-20-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 156925-20-1(Hazardous Substances Data)

156925-20-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 156925-20-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,9,2 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 156925-20:
(8*1)+(7*5)+(6*6)+(5*9)+(4*2)+(3*5)+(2*2)+(1*0)=151
151 % 10 = 1
So 156925-20-1 is a valid CAS Registry Number.

156925-20-1Relevant articles and documents

Synthesis and biological activities of the optical isomers of (±)-4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]me thyl]benzamide (Mosapride)

Morie,Kato,Harada,Yoshida,Matsumoto

, p. 877 - 882 (2007/10/02)

The enantiomers, (S)-(-)-1 and (R)-(+)-1, of (+)-4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]met hyl]benzamide (mosapride) [(+)-1], a new and selective gastroprokinetic agent, were prepared from optically active [4-(4-fluorobenzyl)-2-morpholinyl]methylamines (S)-(-)-4 and (R)-(+)-4, respectively. The requisite (S)-(-)-4 and (R)-(+)-4 were prepared by optical resolution of [4-(4-fluorobenzyl)-2-morpholinyl]methyl p-toluenesulfonate [(+)-5] using (-)- and (+)-N-(p-toluenesulfonyl)glutamic acids, followed by amination of the tosyloxy groupe of (R)-(-)-5 and (S)-(+)-5, respectively. The absolute configurations of (R)-(-)-5 and (S)-(+)-5 were determined on the basis of an asymmetric synthesis of (R)-(-)-5 from (S)-(+)-benzyl glycidyl ether [(S)-(+)-11]. Mosapride and its enantiomers, (S)-(-)-1 and (R)-(+)-1, were essentially equipotent in serotonin 5-HT4 receptor agonistic activity on the electrically evoked contractions in isolated guinea pig ileum.

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