1569270-49-0

Basic information

• Product Name: 9-iodo-N-methyl-N,10-diphenyl-12-azatetracyclo[9.7.0.0^3,8.0^13,18]octadeca-1⁽¹¹⁾,3⁽⁸⁾,4,6,9,13,15,17-octaen-2-amine
• CAS NO: 1569270-49-0
• Molecular Weight: 538.431
• Mol File: 1569270-49-0.mol

Chemical Properties

• CAS DataBase Reference: 9-iodo-N-methyl-N,10-diphenyl-12-azatetracyclo[9.7.0.0^3,8.0^13,18]octadeca-1⁽¹¹⁾,3⁽⁸⁾,4,6,9,13,15,17-octaen-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-iodo-N-methyl-N,10-diphenyl-12-azatetracyclo[9.7.0.0^3,8.0^13,18]octadeca-1⁽¹¹⁾,3⁽⁸⁾,4,6,9,13,15,17-octaen-2-amine(1569270-49-0)
• EPA Substance Registry System: 9-iodo-N-methyl-N,10-diphenyl-12-azatetracyclo[9.7.0.0^3,8.0^13,18]octadeca-1⁽¹¹⁾,3⁽⁸⁾,4,6,9,13,15,17-octaen-2-amine(1569270-49-0)

Safety Data

• Hazardous Substances Data: 1569270-49-0(Hazardous Substances Data)

Upstream product

• 1569270-48-9 N-{(1H-indol-3-yl)[2-(phenylethynyl)phenyl]methyl}-N-methylaniline 

Relevant articles and documents

Molecular iodine-mediated cascade reaction of 2-alkynylbenzaldehyde and indole: An easy access to tetracyclic indoloazulene derivatives

The synthesis of iodo-substituted tetracyclic indole fused azulene derivatives was achieved from the reaction of 2-(substituted phenylethynyl)-benzaldehydes and different indoles in the presence of molecular iodine. The reaction involves the formation of a bisindole from the corresponding 2-(substituted phenylethynyl)benzaldehyde and indole followed by iodocyclization in a one-pot cascade process. A wide range of 2-(substituted phenylethynyl)-benzaldehydes and indoles were utilized in this protocol to derive a diverse range of iodo-substituted tetracyclic indole fused azulene derivatives in moderate to good yields. Further functionalizations of the iodo-substituted tetracyclic indole fused azulenes were achieved by various palladium-catalyzed crosscoupling reactions to generate highly substituted tetracyclic indole fused azulene derivatives.