1569314-60-8

Basic information

• Product Name: 6-(6-([1,1'-biphenyl]-4-ylcarboxamido)-1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)hexanoic acid
• Synonyms: 6-(6-([1,1'-biphenyl]-4-ylcarboxamido)-1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)hexanoic acid
• CAS NO: 1569314-60-8
• Molecular Weight: 492.552
• Mol File: 1569314-60-8.mol

Chemical Properties

• CAS DataBase Reference: 6-(6-([1,1'-biphenyl]-4-ylcarboxamido)-1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(6-([1,1'-biphenyl]-4-ylcarboxamido)-1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)hexanoic acid(1569314-60-8)
• EPA Substance Registry System: 6-(6-([1,1'-biphenyl]-4-ylcarboxamido)-1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)hexanoic acid(1569314-60-8)

Safety Data

• Hazardous Substances Data: 1569314-60-8(Hazardous Substances Data)

Upstream product

• 22952-24-5 6-nitrosaccharin 
• 92-92-2 biphenyl-4-carboxylic acid 
• 1569314-55-1 6-(6-nitro-1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)hexanoic acid 
• 6269-91-6 4-nitrotoluene-2-sulfonamide 

Downstream Products

• 1569314-86-8 N-(2-(6-(hydroxyamino)-6-oxohexyl)-1,1-dioxido-3-oxo-2,3-dihydrobenzo[d]isothiazol-6-yl)-[1,1'-biphenyl]-4-carboxamide 

Relevant articles and documents

Design, synthesis and preliminary bioactivity studies of 1,2-dihydrobenzo[d]isothiazol-3-one-1,1-dioxide hydroxamic acid derivatives as novel histone deacetylase inhibitors

Histone deacetylase (HDAC) is a clinically validated target for antitumor therapy. In order to increase HDAC inhibition and efficiency, we developed a novel series of saccharin hydroxamic acids as potent HDAC inhibitors. Among them, compounds 11e, 11m, 11