156944-07-9Relevant academic research and scientific papers
Facile One Pot Thermal Dehydration and Dethioacetalization of β-Hydroxydithioacetals with Dimethyl sulphoxide: Synthesis of α,β-Unsaturated Aldehydes
Rao, Ch. Srinivasa,Chandrasekharam, M.,Patro, Balaram,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 5783 - 5794 (1994)
The acyclic and cyclic β-hydroxydithioacetals 3a-m and 4a-b obtained by sodium borohydride reduction (or Grignard addition) of the corresponding β-oxodithioacetals 2a-m are shown to undergo facile one pot thermal dehydration and dethioacetalization in the presence of dimethyl sulphoxide to afford the corresponding ene- and polyene aldehydes 5a-m and 6a-b in good yields.The probable mechanism of dethioacetalization with dimethyl sulphoxide has also been discussed.
