1569631-79-3Relevant academic research and scientific papers
A PROCESS FOR THE SYNTHESIS OF OLOPATADINE
-
, (2014/10/03)
The present invention provides a process for the synthesis of olopatadine. Further, the invention discloses a process that results in improved yield of the desired Z isomer.
A simple synthesis of the novel antihistaminic drug olopatadine hydrochloride
Chavan, Subhash P.,Lasonkar, Pradeep B.
, p. 3399 - 3403 (2014/01/06)
A new alternative route for the synthesis of olopatadine is described. The present strategy involves a Lewis acid mediated ring opening of a cyclic ether to introduce 3-(dimethylamino)propylidene group as the side chain. Georg Thieme Verlag Stuttgart . New York.
