1569818-68-3Relevant academic research and scientific papers
FENDILINE DERIVATIVES AND METHODS OF USE THEREOF
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Page/Page column 80, (2014/03/25)
Disclosed herein are novel derivatives of fendiline, including compounds of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives, for example, for the inhibition of K-Ras plasma membrane localization, and compositions thereof, including for the treatment of cancer, are also provided.
