1569899-41-7

Upstream product

• 1569899-39-3 N-(4-((tert-butyldimethylsilyl)oxy)-2-methylenebutyl)-N-(2-((tertbutyldimethylsilyl)oxy)ethyl)-4-methylbenzenesulfonamide 
• 485801-67-0 4-{[tert-butyl(dimethyl)silyl]oxy}-2-methylidenebutan-1-ol 
• 202974-92-3 N-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

Prins cascade cyclization for the synthesis of 1,9-dioxa-4-azaspiro[5.5] undecane derivatives

A novel Prins cascade process for the synthesis of 1,9-dioxa-4- azaspiro[5.5]undecane derivatives by the coupling of aldehydes with N-(4-hydroxy-2-methylenebutyl)-N-(2-hydroxyethyl)-4-methylbenzenesulfonamide has been developed. This is the first report of the synthesis of spiromorpholinotetrahydropyran derivatives through a Prins bicyclization.