1569902-22-2

Upstream product

• 107961-76-2 methyl (3aS,4R,7aR)-4-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,7a-dihydro-4H-[1,3]dioxolo[4,5-c]pyran-6-carboxylate 
• 55697-53-5 methyl 2,4,6-tri-O-benzyl-β-D-galactopyranoside 
• 7757-38-2 2,3:5,6-di-O-isopropylidene-D-mannofuranose 
• 31024-99-4 1,2-dideoxy-4,5:7,8-di-O-isopropylidene-D-erythro-D-manno-1-yno-octitol 
• 1569902-07-3 3,6-di-O-benzyl-1,2-dideoxy-4,5:7,8-di-O-isopropylidene-D-glycero-D-galacto-1-yno-octitol 
• 1569902-08-4 1-bromo-3,6-di-O-benzyl-1,2-dideoxy-4,5:7,8-di-O-isopropylidene-D-glycero-D-galacto-1-yno-octitol 
• 1569902-11-9 methyl [4,5:7,8-di-O-isopropylidene-2,3-O-thionocarbonyl-α-D-glycero-D-galacto-2-octulopyranosyl]onate 

Downstream Products

• 1569902-23-3 methyl 2,4,6-tri-O-benzyl-3-O-[methyl (4,5:7,8-di-O-isopropylidene-3-deoxy-β-D-manno-2-octulopyranosyl)onate]-β-D-glactopyranoside 
• 1569902-32-4 methyl 2,4,6-tri-O-benzyl-3-O-[methyl (7,8-O-isopropylidene-3-deoxy-β-D-manno-2-octulopyranosyl)onate]-β-D-galactopyranoside 
• 1569902-36-8 methyl 2,4,6-tri-O-benzyl-3-O-[methyl (4-O-benzyl-7,8-O-isopropylidene-3-deoxy-β-D-manno-2-octulopyranosyl)onate]-β-D-galactopyranoside 
• 1569902-34-6 C₃₇H₄₆O₁₃ 

Relevant academic research and scientific papers

Preparation of a protected 3-deoxy-d-manno-oct-2-ulosonate glycal donor for the synthesis of β-KDO-containing oligosaccharides

A practical method for the synthesis of KDO glycal donors was developed. The prepared KDO donors exhibited excellent disastereoselectivity of glycosylation in a CH2Cl2-CH3CN solvent mixture, which was found to be associated with the isopropylidene protection at the C-4 and C-5 hydroxyls. The synthetic use of the KDO donor was demonstrated in the preparation of β-KDO-containing oligosaccharides.