1570075-08-9Relevant academic research and scientific papers
Improved synthesis of 4-/6-substituted 2-carboxy-1H-indole-3-propionic acid derivatives and structure-activity relationships as GPR17 agonists
Baqi, Younis,Alshaibani, Samer,Ritter, Kirsten,Abdelrahman, Aliaa,Spinrath, Andreas,Kostenis, Evi,Mueller, Christa E.
, p. 86 - 92 (2014/01/06)
The orphan G protein-coupled receptor GPR17 was shown to be involved in myelin repair and has been proposed as a novel drug target for the treatment of brain and spinal cord injury and for multiple sclerosis. Recently, 3-(2-carboxy-4,6-dichloro-indol-3-yl
