157124-43-1

Basic information

• Product Name: 1-(4-ethoxyphenyl)-1H-tetrazole
• Synonyms: 1-(4-ethoxyphenyl)-1H-tetrazole
• CAS NO: 157124-43-1
• Molecular Weight: 190.205
• Mol File: 157124-43-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-ethoxyphenyl)-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-ethoxyphenyl)-1H-tetrazole(157124-43-1)
• EPA Substance Registry System: 1-(4-ethoxyphenyl)-1H-tetrazole(157124-43-1)

Safety Data

• Hazardous Substances Data: 157124-43-1(Hazardous Substances Data)

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 156-43-4 4-Ethoxyaniline 

Downstream Products

• 238432-78-5 1-(4-ethoxyphenyl)-1H-tetrazol-5-amine 
• 15437-14-6 N-(4-ethoxyphenyl)benzamide 
• 1352545-37-9 5-(3,4,5-trimethoxyphenyl)-1-(4-ethoxyphenyl)-1H-tetrazole 

Relevant articles and documents

A stereocontrolled 1,2-addition reaction of tetrazoles with alkyl propiolates for the synthesis of highly functionalized enamines

A stereocontrolled 1,2-addition reaction of 1-aryl-1H-tetrazoles with alkyl propiolates for the synthesis of highly functionalized enamines was developed. In the presence of silver oxide (Ag2O), the 1,2-addition reaction generated (Z)-N-cyano enamines in good yields with exclusive formation of the Z-isomers. Meanwhile, the 1,2-addition reaction generated (E)-N-cyano enamines in the presence of Ag2O and potassium carbonate (K2CO 3) with high stereoselectivity and yields. Copyright

One-pot syntheses of 5-amino-1-aryltetrazole derivatives

A novel facile route for the introduction of 5-amino and 5-alkylamino substituents into 1-aryltetrazoles has been developed. A range of 5-amino-1-aryltetrazoles was obtained directly from the corresponding 1-aryltetrazoles in one pot by consecutive ring-opening, azidation and intramolecular cyclization. 5-Alkylamino-1-aryltetrazoles were formed by a similar mechanism from 1,4-disubstituted tetrazolium salts. An influence of the nature of aryl substituents and reaction conditions on the regioselectivity of the intramolecular cyclization of intermediate guanyl azides is revealed. Georg Thieme Verlag Stuttgart.