157133-52-3Relevant academic research and scientific papers
Enantioselective Intramolecular Hydroacylation of Unactivated Alkenes: An NHC-Catalyzed Robust and Versatile Formation of Cyclic Chiral Ketones
Janssen-Müller, Daniel,Schedler, Michael,Fleige, Mirco,Daniliuc, Constantin G.,Glorius, Frank
supporting information, p. 12492 - 12496 (2015/10/12)
A highly enantioselective intramolecular N-heterocyclic carbene (NHC)-catalyzed hydroacylation reaction gives access to a range of cyclic ketones from unactivated olefin-substituted aldehydes (up to 99% ee). Remarkably, aliphatic aldehydes were also transformed efficiently in an NHC-catalyzed hydroacylation reaction for the first time. 100% Organic: A highly enantioselective N-heterocyclic carbene (NHC)-catalyzed intramolecular hydroacylation of aromatic and, more interestingly, aliphatic aldehydes with unactivated olefins offers access to a range of cyclic α-chiral ketones bearing quaternary centers. The reaction was found to be highly robust and proceeds with excellent yield in the presence of a diverse range of functional groups.
Synthesis of Diastereoisomeric 2-Benzyl-1,2-diphenylindans
Alesso, Elba N.,Bianchi, Daniel E.,Iglesias, Graciela Y. Moltrasio,Sierra, Manuel Gonzalez,Aguirre, Jose M.
, p. 1237 - 1248 (2007/10/02)
The diastereomeric 2-benzyl-1,2-diphenylindan-1-ols were prepared and subjected to deoxygenation reactions under a variety of conditions to obtain 2-benzyl-1,2-diphenylindan.The stereochemistry of these compounds has been characterized on the basis of che
