157148-06-6 Usage
Uses
Used in Agriculture:
Harzianic acid is used as a natural pesticide or fungicide for its insecticidal, antifungal, and antibacterial properties, providing an eco-friendly alternative to synthetic chemicals.
Used in Medicine:
1. Anticancer Applications:
Harzianic acid is used as an anticancer agent for its cytotoxic effects against certain cancer cell lines, offering a potential therapeutic option for cancer treatment.
2. Drug Delivery Systems:
Harzianic acid can be incorporated into drug delivery systems to enhance its bioavailability and therapeutic outcomes, particularly in the context of cancer treatment. Various organic and metallic nanoparticles can be employed as carriers for harzianic acid delivery, aiming to improve its efficacy and targeting specific cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 157148-06-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,1,4 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 157148-06:
(8*1)+(7*5)+(6*7)+(5*1)+(4*4)+(3*8)+(2*0)+(1*6)=136
136 % 10 = 6
So 157148-06-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H27NO6/c1-5-6-7-8-9-10-14(21)15-16(22)13(20(4)17(15)23)11-19(26,12(2)3)18(24)25/h7-10,12-13,23,26H,5-6,11H2,1-4H3,(H,24,25)/b8-7+,10-9+
157148-06-6Relevant academic research and scientific papers
Healy, Alan R.,Vinale, Francesco,Lorito, Matteo,Westwood, Nicholas J.
, p. 692 - 695 (2015)
The bioactive natural product harzianic acid was prepared for the first time in just six steps (longest linear sequence) with an overall yield of 22%. The identification of conditions to telescope amide bond formation and a Lacey-Dieckmann reaction into one pot proved important. The three stereoisomers of harzianic acid were also prepared, providing material for comparison of their biological activity. While all of the isomers promoted root growth, improved antifungal activity was unexpectedly associated with isomers in the enantiomeric series opposite that of harzianic acid.
