1571911-15-3

Basic information

• Product Name: 4-((4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)phenoxy)methyl)-1-benzyl-1H-1,2,3-triazole
• Synonyms: 4-((4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)phenoxy)methyl)-1-benzyl-1H-1,2,3-triazole
• CAS NO: 1571911-15-3
• Molecular Weight: 452.516
• Mol File: 1571911-15-3.mol

Chemical Properties

• CAS DataBase Reference: 4-((4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)phenoxy)methyl)-1-benzyl-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)phenoxy)methyl)-1-benzyl-1H-1,2,3-triazole(1571911-15-3)
• EPA Substance Registry System: 4-((4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)phenoxy)methyl)-1-benzyl-1H-1,2,3-triazole(1571911-15-3)

Safety Data

• Hazardous Substances Data: 1571911-15-3(Hazardous Substances Data)

Upstream product

• 34596-36-6 1,4-bis(prop-2-yn-1-yloxy)benzene 
• 622-79-7 benzyl azide 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Synthesis of a novel resorcin[4]arene-glucose conjugate and its catalysis of the CuAAC reaction for the synthesis of 1,4-disubstituted 1,2,3-triazoles in water

The Cu(i)-catalyzed azide-alkyne cycloaddition (CuAAC) in aqueous media using resorcin[4]arene glycoconjugate (RG) is reported. The eight β-d-glucopyranoside moieties constructed on the resorcin[4]arene upper rim provide a pseudo-saccharide cavity that offers a suitable host environment for water-insoluble hydrophobic azido and/or alkyne substrates in water. The utility of RG was established as an efficient inverse phase transfer catalyst for the CuAAC in water as a green approach for the synthesis of 1,4-disubstituted 1,2,3-triazole species. The catalytic utility of RG (1 mol%) was demonstrated in a multicomponent one-pot CuAAC for various azido/alkyne substrates. The RG acts as a molecular host and a micro-reactor resulting in the 1,4-disubstituted 1,2,3-triazoles in excellent yield.

Supported CuBr on graphene oxide/Fe3O4: A highly efficient, magnetically separable catalyst for the multi-gram scale synthesis of 1,2,3-triazoles

A superparamagnetic graphene oxide (GO)/Fe3O4-CuBr catalyst was prepared via a simple chemical method and characterized by Fourier transform infrared (FTIR), thermal gravimetric analysis (TGA), transmission electron microscopy (TEM), powder X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The GO/Fe3O4-CuBr catalyst could be dispersed homogeneously in water and further used as an excellent semi-heterogeneous catalyst for the one-pot multi-component Cu(i)-catalyzed azide-alkyne 1,3-dipolar cycloaddition (CuAAC) reaction. 1,4-Disubstituted mono/bis-1,2,3-triazoles are readily obtained on a multi-gram scale by the reaction of aryl/alkyl halides, alkynes and sodium azide under microwave irradiation conditions in good to excellent yields. Moreover, GO/Fe3O4-CuBr could be separated conveniently from the reaction mixtures by an external permanent magnet and reused in at least six consecutive runs without a noticeable drop in the product yield and its catalytic activity.