157198-79-3

Basic information

• Product Name: 2-(1H-BENZIMIDAZOL-1-YL)PROPANOIC ACID
• Synonyms: BAS 07033704;ChemDiv2_002979;EC-000.1372;Oprea1_647829;Oprea1_710774;ZERO/006422;1H-Benzimidazole-1-aceticacid,alpha-methyl-(9CI);1H-benzimidazole-1-acetic acid, alpha-methyl-
• CAS NO: 157198-79-3
• Molecular Formula: C10H10N2O2
• Molecular Weight: 190.1986
• Product Categories: BENZIMIDAZOLE;Imidazol&Benzimidazole
• Mol File: 157198-79-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 180 °C
• Boiling Point: 391 °C at 760 mmHg
• Flash Point: 190.3 °C
• Appearance: /
• Density: 1.3 g/cm³
• Vapor Pressure: 8.16E-07mmHg at 25°C
• Refractive Index: 1.633
• PKA: 3.43±0.10(Predicted)
• CAS DataBase Reference: 2-(1H-BENZIMIDAZOL-1-YL)PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-BENZIMIDAZOL-1-YL)PROPANOIC ACID(157198-79-3)
• EPA Substance Registry System: 2-(1H-BENZIMIDAZOL-1-YL)PROPANOIC ACID(157198-79-3)

Safety Data

• Hazardous Substances Data: 157198-79-3(Hazardous Substances Data)

Usage

General Description

2-(1H-benzimidazol-1-yl)propanoic acid, also known as BZP, is a synthetic chemical compound that is structurally related to the neurotransmitter serotonin. It is classified as a psychoactive substance and has been used as a recreational drug due to its stimulant and hallucinogenic effects. BZP is known to activate the release of serotonin and dopamine in the brain, leading to increased energy, euphoria, and altered perception. However, it is associated with negative side effects such as insomnia, anxiety, and increased heart rate. The use and distribution of BZP have been regulated in many countries due to its potential for misuse and harm to health.

InChI:InChI=1/C10H10N2O2/c1-7(10(13)14)12-6-11-8-4-2-3-5-9(8)12/h2-7H,1H3,(H,13,14)

Upstream product

• 51-17-2 benzoimidazole 
• 598-78-7 (R,S)-2-chloropropionic acid 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY

This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

Hetrocyclic systems containing azindole: Synthesis and pharmacological screening of 1-(H/bromo/chloro/nitro/methyl substituted phenyloxy)acetyl/propionyl>benzimidazoles

Benzimidazole on treatment with α-chloroacetic or propionic acid gives benzimidazole-1-acetic or propionic acid (1a/1b) which on refluxing with thionyl chloride affords the corresponding chloride (2a/2b).The chlorides 2a,b react with bromo, chloro, nitro