1572012-87-3

Basic information

• Product Name: C₂₂H₂₃ClN₂S
• Synonyms: C₂₂H₂₃ClN₂S
• CAS NO: 1572012-87-3
• Molecular Weight: 382.957
• Mol File: 1572012-87-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₃ClN₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₃ClN₂S(1572012-87-3)
• EPA Substance Registry System: C₂₂H₂₃ClN₂S(1572012-87-3)

Safety Data

• Hazardous Substances Data: 1572012-87-3(Hazardous Substances Data)

Upstream product

• 17223-45-9 8-chloro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 

Relevant articles and documents

COMPOUNDS AND METHODS FOR TREATMENT OF HYPERTENSION

Hydrogenated pyrido[4,3-b]indoles, pyrido[3,4-b]indoles and azepino[4,5-b]indoles are described. The compounds may bind to and are adrenergic receptor α2B antagonists. The compounds may also bind to and antagonize adrenergic receptor α1B. The compounds may find use in therapy, e.g., to (i) reduce blood pressure and/or (ii) promote renal blood flow and/or (iii) decrease or inhibit sodium reabsorption. The compounds may also be used to treat diseases or conditions that are, or are expected to be, responsive to a decrease in blood pressure. Use of the compounds to treat cardiovascular and renal disorders is particularly described.