15725-16-3Relevant academic research and scientific papers
Divergent Domino Reactions of Prop-2-ynylsulfonium Salts: Access to Sulfur-Containing Benzo-Fused Dioxabicyclo[3.3.1]nonanes and Dihydrofuro[2,3- c]chromenes
Zhou, Yiming,Chen, Yu,Huang, You
, p. 5941 - 5946 (2020)
Solvent-controlled divergent domino annulation reactions between 2-hydroxy-2-methylchromene derivatives and prop-2-ynylsulfonium salts have been developed. Specifically, a sequential [4 + 2] and [4 + 2] annulation reaction occurred in 1,2-dichloroethane affording sulfur-containing benzo-fused dioxabicyclo[3.3.1]nonanes. In contrast, by changing the solvent to toluene, the reaction course switched to a [4 + 2] and [4 + 1] annulation reaction to afford dihydrofuro[2,3-c]chromenes. It is noteworthy that the prop-2-ynylsulfonium salt participates in the transformation with its γ-carbon atom for the first time.
Base-Promoted Tandem Cyclization for the Synthesis of Benzonitriles by C?C Bond Construction
Zhu, Cheng-Zhi,Wei, Yin,Shi, Min
supporting information, p. 808 - 813 (2018/01/27)
A facile synthesis of benzonitriles via a base-promoted tandem cyclization reaction of α,β-unsaturated enones having electron-withdrawing group (EWG) and 2-acyl-acrylonitriles was developed. This new synthetic method to access benzonitriles is suitable for a wide range of substrates. A plausible reaction mechanism is proposed on the basis of previous literature and our own investigations. (Figure presented.).
Synthesis, spectral studies and antimicrobial activity of 7-chloro-2-alkyl/aryl-4-alkyl/aryl-3-arylidene-3H-1,5-benzodiazepines
Pathak, Vijai N.,Joshi, Rahul,Gupta, Neetu
, p. 1191 - 1197 (2008/09/19)
Condensation of various β-diketones 2 with appropriate araldehydes 1 in the presence of piperidene has afforded 2-arylidene-1,3-diketones 3 which in turn on condensation with 4-chloro-1,2-phenylene diamine in acidic medium give a series of 7-chloro-2-alky
