15728-34-4

Basic information

• Product Name: (3-ethoxy-4-hydroxybenzylidene)propanedinitrile
• Synonyms: (3-Ethoxy-4-hydroxybenzylidene)malononitrile; propanedinitrile, 2-[(3-ethoxy-4-hydroxyphenyl)methylene]-
• CAS NO: 15728-34-4
• Molecular Formula: C₁₂H₁₀N₂O₂
• Molecular Weight: 214.22
• Mol File: 15728-34-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 390.5°C at 760 mmHg
• Flash Point: 190°C
• Density: 1.242g/cm³
• Vapor Pressure: 1.17E-06mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: (3-ethoxy-4-hydroxybenzylidene)propanedinitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (3-ethoxy-4-hydroxybenzylidene)propanedinitrile(15728-34-4)
• EPA Substance Registry System: (3-ethoxy-4-hydroxybenzylidene)propanedinitrile(15728-34-4)

Safety Data

• Hazardous Substances Data: 15728-34-4(Hazardous Substances Data)

Usage

General Description

(3-ethoxy-4-hydroxybenzylidene)propanedinitrile, also known as EHPN, is a synthetic compound with potential antimicrobial and anti-inflammatory properties. It is a derivative of 3-ethoxy-4-hydroxybenzaldehyde and propanedinitrile, and has been studied for its potential use in pharmaceuticals and agrochemicals. EHPN has shown promise in inhibiting the growth of bacteria and fungi, making it a potential candidate for use as an antimicrobial agent. Additionally, it has also demonstrated anti-inflammatory effects, indicating its potential utility in the treatment of inflammatory conditions. Further research and development of EHPN may lead to its application in various industries for its beneficial properties.

Upstream product

• 905406-44-2 C₁₇H₁₇NO₃ 
• 109-77-3 malononitrile 
• 121-32-4 4-hydroxy-3-ethoxybenzaldehyde 

Relevant articles and documents

Knoevenagel condensation reaction on a new highly-efficient La2O2CO3-TiO2 mixed oxide catalyst: Composition-effects on C[dbnd]C bond formation

The highly efficient catalytic abilities of some mixed oxides are due to cooperative interactions between acid and base functional groups present in their active sites. New La2O2CO3-TiO2 mixed oxide catalysts wi

Chemoselective reaction of malononitrile with imine-ones and antifungal potential of products

Condensation of malononitrile with 1-[4-(benzylideneamino.-phenyl]efhanones 1-10, the compounds containing both carbonnitrogen and carbon-oxygen double bonds, in equimolar ratio results in the formation of solid products, identified as-benzylidenemalononitrile and its derivatives 1a-10a on the basis of elemental analysis and spectral studies. The reaction of 1-10 with two moles of malononitrile also yields the same products 1a-10a by a chemoselective attack of malononitrile on carbonnitrogen double bond only rather than on both the reactive centres. The synthesized compounds 1a-10a have been evaluated for antifungal potential against Alternaria alternata, Colletotrichum capsici, Fusarium oxysporum, Myrothecium roridum and Ustilago tritici. Some of the compounds have been found to possess promising antifungal potential against the test fungi.