1572984-82-7Relevant academic research and scientific papers
Photocleavable dimerizer for the rapid reversal of molecular trap antagonists
Ahmed, Shubbir,Xie, Jun,Horne, David,Williams, John C.
, p. 4546 - 4552 (2014)
Background: The ability to rapidly turn on and off an acute antagonist is helpful to understand the initiation of a cellular program. Results: Aphotocleavable analog was produced and functionally demonstrated. Conclusion: Fine temporal control of endosome dispersion and restoration was obtained. Significance: The combination of traps and the photocleavable analog permits new avenues to study signaling within a single cell in an organism.
Photocleavable linker
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Page/Page column 19-22, (2015/09/22)
There are provided, inter alia, photolabile compounds and methods useful for the formation of dimers of biological molecules and subsequent dissociation of the dimers.
