Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate, also known as Dutasteride EP Impurity C, is a synthetic compound derived from azasteroids. It is characterized by its ability to inhibit key components of the male hormonal system, specifically 5α-reductase and androgen receptor binding.
157307-36-3
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Basic information
- Product Name: Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
- Synonyms: Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate;Dutasteride EP Impurity C;AHSRUURQZYMTKR-FKLRSJPUSA-N;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-ethyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate
- CAS NO:157307-36-3
- Molecular Formula: C21H31NO3
- Molecular Weight: 345.47574
- EINECS: N/A
- Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
- Mol File: 157307-36-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 489.9±45.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.099±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: -20°C Freezer, Under inert atmosphere
- Solubility: Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
- PKA: 14.16±0.70(Predicted)
- CAS DataBase Reference: Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate(CAS DataBase Reference)
- NIST Chemistry Reference: Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate(157307-36-3)
- EPA Substance Registry System: Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate(157307-36-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 157307-36-3(Hazardous Substances Data)
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157307-36-3 Usage
Uses
Used in Pharmaceutical Industry:Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate is used as a pharmaceutical compound for the inhibition of 5α-reductase and androgen receptor binding. These are major effecters in the male hormonal system, and their inhibition can be beneficial in treating conditions related to androgen excess or hormone-sensitive disorders.
Used in Hormonal Regulation:
Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate is used as a hormonal regulator, targeting the male hormonal system by inhibiting 5α-reductase and androgen receptor binding. This can help in managing conditions where hormonal imbalances play a significant role, such as benign prostatic hyperplasia (BPH) and androgenetic alopecia (male pattern baldness).
Used in Research and Development:
Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate is also used in research and development for the study of hormonal systems, particularly in the context of male reproductive health and the development of new therapeutic strategies for hormone-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 157307-36-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,3,0 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.Calculate Digit Verification of CAS Registry Number 157307-36:
(8*1)+(7*5)+(6*7)+(5*3)+(4*0)+(3*7)+(2*3)+(1*6)=133
133 % 10 = 3
So 157307-36-3 is a valid CAS Registry Number.
157307-36-3Upstream product
157307-36-3Downstream Products
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Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
