157327-49-6 Usage
General Description
5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, also known as THPP, is a heterocyclic compound consisting of a pyrido-pyrimidine ring system. It is a synthetic chemical that has been studied for its potential pharmaceutical applications, particularly in the field of neuroscience. THPP has shown promise as a ligand for various neurotransmitter receptors, including the alpha7 nicotinic acetylcholine receptor and the 5-HT3 receptor. It has also been investigated for its potential as a modulator of voltage-gated ion channels. Additionally, THPP has been suggested as a potential scaffold for the development of novel therapeutic agents. Research on THPP and its derivatives continues to explore their pharmacological properties and potential medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 157327-49-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,3,2 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 157327-49:
(8*1)+(7*5)+(6*7)+(5*3)+(4*2)+(3*7)+(2*4)+(1*9)=146
146 % 10 = 6
So 157327-49-6 is a valid CAS Registry Number.
157327-49-6Relevant articles and documents
Synthesis of the bicyclic secondary amines via dimethylaminomethylene ketones from 3-pyrrolidone and 4-piperidone
Fukui, Hideto,Inoguchi, Kiyoshi,Nakano, Jun
, p. 257 - 264 (2002)
The reaction of N-protected 3-pyrrolidone and 4-piperidone with N,N-dimethylformamide dimethyl acetal gave the dimethylaminomethylene ketones, which reacted with several types of hydrazines, amidines, and guanidine to afford the secondary amines having fused ring system.
