15733-09-2

Basic information

• Product Name: 1-methoxy-4-((methylsulfinyl)methyl)benzene
• Synonyms: 1-methoxy-4-((methylsulfinyl)methyl)benzene
• CAS NO: 15733-09-2
• Molecular Weight: 184.259
• Mol File: 15733-09-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-methoxy-4-((methylsulfinyl)methyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-4-((methylsulfinyl)methyl)benzene(15733-09-2)
• EPA Substance Registry System: 1-methoxy-4-((methylsulfinyl)methyl)benzene(15733-09-2)

Safety Data

• Hazardous Substances Data: 15733-09-2(Hazardous Substances Data)

Upstream product

• 67-68-5 dimethyl sulfoxide 
• 824-94-2 p-methoxybenzyl chloride 
• 2746-25-0 p-Methoxybenzyl bromide 
• 5925-86-0 2-Methoxy-5-methylsulfanylmethyl-cyclohexa-1,3-diene 
• 5925-86-0 (4-methoxybenzyl)methylsulfide 

Downstream Products

• 824-94-2 p-methoxybenzyl chloride 

Relevant articles and documents

Methanesulfinylation of Benzyl Halides with Dimethyl Sulfoxide

A phenyltrimethylammonium tribromide-mediated nucleophilic substitution/oxygen transformation reaction of benzyl halides with DMSO has been developed. In this transition-metal-free reaction, DMSO acts as not only a solvent but also a "S(O)Me" source, thus providing a convenient method for the efficient and direct synthesis of various benzyl methyl sulfoxides.

An Efficient Asymmetric Oxidation of Sulfides to Sulfoxides

The Sharpless reagent for asymmetric epoxidation was modified by addition of 1 mol equiv of H2O to give a new homogenous reagent (Ti(O-i-Pr)4/diethyl tartrate/H2O/t-BuOOH = 1:2:1:1).This reagent cleanly oxidizes prochiral functionalized sulfides into optically active sulfoxides.The observed ee mainly ranged between 75 and 90percent for alkyl aryl sulfoxides and 50-71percent for dialkyl sulfoxides.A strong temperature dependence on ee was also observed in the asymmetric oxidation of methyl p-tolyl sulfoxide.