157331-14-1Relevant academic research and scientific papers
Highly effective procedure for introduction of amino group into the 2-position of imidazole ring
Kawasaki, Ikuo,Taguchi, Norio,Yoneda, Youko,Yamashita, Masayuki,Ohta, Shunsaku
, p. 1375 - 1379 (2007/10/03)
Procedures for the preparation of 2-amino- and 2-arylaminobenzimidazoles were developed, and one of the efficient procedure was applied to the synthesis of preclathridine A, a marine imidazole alkaloid isolated from a sponge.
Introduction of carbogenic substituent into the 4-position of 1-methyl-1H-imidazole
Ohta,Yamamoto,Kawasaki,Yamashita,Nagashima,Yoshikawa
, p. 821 - 825 (2007/10/02)
The 4-position of the 1-methyl-1H-imidazole ring was lithiated by treatment of the corresponding 4-bromo derivatives with tert-butyllithium. This procedure was applied to synthesis of the left-hand part of pyronaamidine (1), which is a biologically intere
