157331-32-3Relevant academic research and scientific papers
Total synthesis of kealiiquinone, an imidazole marine alkaloid
Kawasaki, Ikuo,Taguchi, Norio,Yamashita, Masayuki,Ohta, Shunsaku
, p. 1393 - 1398 (2007/10/03)
The total synthesis of kealiiquinone (1), a highly substituted imidazole marine alkaloid isolated from sponge, was achieved via nine reaction steps starting from 1-methyl-1H-imidazole (5). The synthesis is based on the selective introduction of appropriat
Introduction of carbogenic substituent into the 4-position of 1-methyl-1H-imidazole
Ohta,Yamamoto,Kawasaki,Yamashita,Nagashima,Yoshikawa
, p. 821 - 825 (2007/10/02)
The 4-position of the 1-methyl-1H-imidazole ring was lithiated by treatment of the corresponding 4-bromo derivatives with tert-butyllithium. This procedure was applied to synthesis of the left-hand part of pyronaamidine (1), which is a biologically intere
