157333-16-9Relevant academic research and scientific papers
Synthesis of Dopamines Labelled with 13C in the α- or β-Side Chain Position and Their Application to Structural Studies on Melanins by Solid-State NMR Spectroscopy
Crescenzi, Orlando,Kroesche, Christoph,Hoffbauer, Wilfried,Jansen, Martin,Napolitano, Alessandra,et al.
, p. 563 - 568 (2007/10/02)
Solid-state NMR spectroscopy was applied to the analysis of melanins prepared by peroxidase-H2O2 oxidation of dopamines specifically 13C labelled in the α- or β-side chain positions.A surprisingly diverse pattern of signals indicated the presence of uncyclized dopamine and noradrenaline-derived units, in addition to indole and carbonyl carbon atoms.These structural features, coupled with the results obtained from elemental analysis of dopamine melanin samples prepared under different conditions, point to a pigment formation process more complex than previously believed. - Key Words: CP-MAS NMR Spectroscopy / Melanin / Oxidative phenolic coupling / Quinone methides / Labelled compounds, 13C / Dopamines / Enzymes
