15737-67-4Relevant academic research and scientific papers
In-situ nickel(II) complexes of 3-(dimethylamino)-1-propylamine based Schiff base ligands: Structural, electrochemical, biomolecular interaction and antimicrobial properties
Jayamani, Arumugam,Nagasubramanian, Soundarajan,Thamilarasan, Vijayan,Ojwach, Stephen O.,Gopu, Gopalakrishnan,Sengottuvelan, Nallathambi
, p. 791 - 799 (2018)
Five new di-Schiff base nickel(II) complexes (1–5) of salen type ligands were synthesized in-situ by condensation of 3-(dimethylamino)-1-propylamine with 2-hydroxybenzaldehyde, 2-hydroxy-5-methyl benzaldehyde, 2-hydroxy-5-bromo benzaldehyde, 2-hydroxy-5-nitrobenzaldehyde and 2-hydroxy-1-naphthaldehyde to obtain L1–L5, respectively and complexed with nickel chloride. Single crystal X-ray diffraction studies of complexes 1 and 5 showed a distorted octahedral and distorted square-planar geometry, respectively around nickel atoms. The cyclic voltammetry of complexes 1–5 showed redox peaks near cathodic and anodic regions assignable to the Ni2+/Ni+ and Ni2+/Ni3+ redox couples, respectively. The binding studies of complexes with calf thymus DNA (ctDNA) showed an intercalation mode of binding. The nuclease activity of the complexes with pBR322 plasmid DNA showed efficient oxidative cleavage by the formation of singlet oxygen species in presence of H2O2. All nickel(II) complexes were found to have greater zone inhibition diameter when analyzed for antimicrobial property against four bacterial species and two human pathogenic fungal species.
Structural interconversions of octahedral, planar, and tetrahedral nickel(II) complexes
Chakravortv,Fennessey,Holm
, p. 26 - 33 (2008/10/08)
A series of bis(N-R-salicylaldimine)nickel(II) complexes has been prepared in which the R group contains a site capable of coordination. Complexes with R = CH3CHCH2OCH3 but differing in the extent and position of chelate ring substitution have been thoroughly studied. For these complexes it has been shown from measurement of ligand field spectra and proton contact shifts that in the temperature range -40 to 50° in chloroform solution discrete octahedral, planar, and tetrahedral stereoisomers are present in equilibrium. At low temperatures the octahedral form predominates; at higher temperatures the equilibrium is displaced toward the planar and tetrahedral forms. For two complexes the temperature dependence of the distribution of stereoisomers has been estimated from spectral data. The spectra of the octahedral complexes were found to be quite similar to those of associated paramagnetic bis(salicylaldimine)nickel(II), suggesting quasi-octahedral coordination in the latter. The spin density distributions in the coordinated ligand systems were shown to be similar in sign in the octahedral and tetrahedral stereoisomers.
