157425-54-2Relevant articles and documents
NOVEL PYRROLE DERIVATIVES FOR THE TREATMENT OF CANCER
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Page/Page column 39, (2014/10/15)
The invention provides a method for the treatment of cancer, which method comprises the general formula (I) wherein R1, R2, R3, R4 and W are as described herein.
Total Synthesis of an Antitumor Antibiotic, (+/-)-Duocarmycin SA
Muratake, Hideaki,Abe, Itsuko,Natsume, Mitsutaka
, p. 2573 - 2576 (2007/10/02)
A 12-step total synthesis of (+/-)-duocarmycin SA (1) was achieved from a readily available pyrrole 3 by way of 7,10/11,14 and 18, using a SnCl2-mediated reaction of a singlet oxygen adduct 6 with 5, as well as the Heck and Mitsunobu reactions on 9 and 16 as key steps.