157429-42-0 Usage
General Description
"(R)-4-Mercapto-2-pyrrolidone" is a chemical compound also known as raloxifene. It is an inhibitor of the aromatase enzyme, which is involved in the production of estrogen. (R)-4-Mercapto-2-pyrrolidone has been studied for its potential use in the treatment of breast cancer and other hormone-related conditions. It is also known for its ability to bind to estrogen receptors and modulate their activity, which can have implications for hormone therapy. Additionally, raloxifene has been investigated for its potential as a neuroprotective agent due to its ability to reduce oxidative damage and inflammation in the brain. Overall, "(R)-4-Mercapto-2-pyrrolidone" has diverse potential applications in the fields of oncology, endocrinology, and neurology.
Check Digit Verification of cas no
The CAS Registry Mumber 157429-42-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,4,2 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 157429-42:
(8*1)+(7*5)+(6*7)+(5*4)+(4*2)+(3*9)+(2*4)+(1*2)=150
150 % 10 = 0
So 157429-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H7NOS/c6-4-1-3(7)2-5-4/h3,7H,1-2H2,(H,5,6)/t3-/m1/s1
157429-42-0Relevant articles and documents
Trials for the synthesis of (R)-4-mercapto-pyrrolidin-2-one ((R)-MPD)
Kobayashi, Satoshi,Kobayashi, Katsuhiro,Hirai, Koichi
, p. 909 - 912 (2007/10/03)
Several trials were made for the syntheses of (S)-4-hydroxy-pyrrolidin- 2-one ((S)-HPD) and (R)-4-mercapto-pyrrolidin-2-one ((R)-MPD), a substituent at the 2-position of the orally active carbapenem antibiotic CS-834. The latter was synthesized from prochiral dimethyl or diethyl 3-p- methoxybenzylthioglutarate using pig liver esterase technology to give monoester with an optical purity of 51-71% e.e. as a key intermediate.
