1574334-62-5

Basic information

• Product Name: (E)-benzyl-14-((4S,5R)-2,2-dimethyl-5-((R)-oxiran-2-yl)-1,3-dioxolan-4-yl)tetradec-13-enoate
• Synonyms: (E)-benzyl-14-((4S,5R)-2,2-dimethyl-5-((R)-oxiran-2-yl)-1,3-dioxolan-4-yl)tetradec-13-enoate
• CAS NO: 1574334-62-5
• Molecular Weight: 458.638
• Mol File: 1574334-62-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-benzyl-14-((4S,5R)-2,2-dimethyl-5-((R)-oxiran-2-yl)-1,3-dioxolan-4-yl)tetradec-13-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-benzyl-14-((4S,5R)-2,2-dimethyl-5-((R)-oxiran-2-yl)-1,3-dioxolan-4-yl)tetradec-13-enoate(1574334-62-5)
• EPA Substance Registry System: (E)-benzyl-14-((4S,5R)-2,2-dimethyl-5-((R)-oxiran-2-yl)-1,3-dioxolan-4-yl)tetradec-13-enoate(1574334-62-5)

Safety Data

• Hazardous Substances Data: 1574334-62-5(Hazardous Substances Data)

Upstream product

• 67400-04-8 Δ¹³-tetradecenol 
• 1611-56-9 1-Bromo-11-hydroxyundecane 
• 23568-31-2 2,3:4,5-di-O-isopropylidene-L-arabinose 
• 7331-03-5 13-tetradecenoic acid 
• 85896-31-7 tetradec-13-enal 
• 1225281-87-7 C₂₀H₄₂OSi 
• 98008-53-8 11-(dimethyl-t-butylsilyloxy)undecyl bromide 
• 1574334-59-0 (S)-1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 22893-94-3 (4R,5S)-4-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-5-vinyl-1,3-dioxolane 
• 92936-93-1 (4R,5S)-4-(bis(ethylthio)methyl)-5-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-1,3-dioxolane 
• 1574334-34-1 benzyl tetradec-13-enoate 
• 1574334-36-3 (S)-2-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)-2-hydroxyethyl-4-methylbenzenesulfonate 

Downstream Products

• 1574334-69-2 C₄₂H₆₄O₇ 
• 1574334-73-8 C₅₅H₇₇NO₁₀ 
• 1574334-65-8 C₄₈H₇₈O₇Si 

Relevant articles and documents

The first convergent total synthesis of penarolide sulfate A2, a novel α-glucosidase inhibitor

Penarolide sulfate A2, a 31-membered macrolide encompassing a proline residue and three sulfate groups, was firstly synthesized in 16 linear steps with 4.8% overall yield. Three consecutive stereogenic centers in penarolide sulfate A2 were efficiently derived from natural chiral template l-arabinose. The crucial assembly reactions included Brown asymmetric allylation, olefin cross-metathesis, alkyne-epoxide coupling, and macrolactamization. The anti-yeast α-glucosidase activities of penarolide sulfate A2 and its fully desulfated derivative were examined showing IC50 values of 4.87 and 10.74 μg mL-1, respectively.