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Usage

Uses

Used in Food Industry:
2-(4-tert-Butyl-phenyl)-2-Methyl-propionic acid Methyl ester is used as an antioxidant for preserving the quality and freshness of various food products. It helps to prevent oxidation, which can lead to spoilage and deterioration, thereby extending the shelf life of these products.
Used in Cosmetics Industry:
2-(4-tert-Butyl-phenyl)-2-Methyl-propionic acid Methyl ester is used as an antioxidant in cosmetics to protect the products from oxidation and degradation, ensuring their stability and effectiveness. It helps to maintain the quality and performance of cosmetic products, providing consumers with a longer-lasting and more reliable product experience.
Used in Plastics and Rubber Industry:
2-(4-tert-Butyl-phenyl)-2-Methyl-propionic acid Methyl ester is used as a stabilizer in the production of plastics and rubber to prevent degradation caused by oxidation. This helps to improve the durability and longevity of these materials, making them more resistant to wear and tear.
Used in Pharmaceutical Industry:
2-(4-tert-Butyl-phenyl)-2-Methyl-propionic acid Methyl ester is used as an antioxidant in the pharmaceutical industry to protect active ingredients from oxidation, ensuring the stability and efficacy of medications. This helps to maintain the quality and effectiveness of pharmaceutical products, providing patients with reliable and consistent treatment options.

Upstream product

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Relevant academic research and scientific papers

Palladium-catalyzed α-arylation of zinc enolates of esters: Reaction conditions and substrate scope

The intermolecular α-arylation of esters by palladium-catalyzed coupling of aryl bromides with zinc enolates of esters is reported. Reactions of three different types of zinc enolates have been developed. α-Arylation of esters occurs in high yields with i

Arylation of esters catalyzed by the Pd(I) dimer {[P(t-Bu)]PdBr}

Conditions for the coupling of bromoarenes with esters using a single base and catalyst with improved turnover numbers are described. These general conditions were made possible by using the Pd(l) catalyst {[P(f-Bu) 3]PdBr}2. Reactions of acetates, propionates, and isobutyrates are presented, and reactions of all three classes of esters on a 10 g scale are described.

Efficient synthesis of α-aryl esters by room-temperature palladium-catalyzed coupling of aryl halides with ester enolates

A catalytic amount of Pd(dba)2 ligated by either carbene precursor N,N′-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazolium (1) or P(t-Bu)3 mediated the coupling of aryl halides and ester enolates to produce α-aryl esters in high yields at room temperature. The reaction was highly tolerant of functionalities and substitution patterns on the aryl halide. Improved protocols for the selective monoarylation of tert-butyl acetate and the efficient arylation of α,α-disubstituted esters were developed with LiNCy2 as base and P(t-Bu)3 as ligand. In addition, tert-butyl esters, such as those of Naproxen and Flurbiprofen, were prepared from tert-butyl propionate and aryl bromides in high yields in the presence of Pd(dba)2 and the hindered, saturated heterocyclic carbene ligand precursor.