1574486-26-2

Basic information

• Product Name: 5-hydroxy-5-(4-methoxyphenyl)-3,4-dimethyl-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one
• Synonyms: 5-hydroxy-5-(4-methoxyphenyl)-3,4-dimethyl-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one
• CAS NO: 1574486-26-2
• Molecular Weight: 310.353
• Mol File: 1574486-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-5-(4-methoxyphenyl)-3,4-dimethyl-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-5-(4-methoxyphenyl)-3,4-dimethyl-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one(1574486-26-2)
• EPA Substance Registry System: 5-hydroxy-5-(4-methoxyphenyl)-3,4-dimethyl-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one(1574486-26-2)

Safety Data

• Hazardous Substances Data: 1574486-26-2(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 40274-33-7 3,4-dimethyl-N-(2-pyridyl)maleinimid 
• 93296-09-4 4-methoxyphenylzinc chloride 
• 97302-05-1 di-4-methoxyphenylzinc 

Relevant articles and documents

Efficient access to 3-substituted-γ-hydroxylactams: The uncatalyzed addition of diorganozinc reagents to cyclic imides with heterocyclic substitution

A range of 3-substituted-γ-hydroxylactams have been prepared via the uncatalyzed addition of organozinc nucleophiles to cyclic imides. This reactivity is primarily limited to imides containing heterocyclic N-substitution, but proceeds efficiently with a variety of diorganozinc reagents, including those prepared and utilized without purification, as well as organozinc halides. It is hypothesized that the presence of a Lewis basic directing group is required for optimum reactivity.