1574664-80-4Relevant academic research and scientific papers
Efficient catalytic-free method to produce α-aryl cycloalkanones through highly chemoselective coupling of aryl compounds with oxyallyl cations
Luo, Juan,Zhou, Hui,Hu, Jiwei,Wang, Rui,Tang, Qiang
, p. 17370 - 17377 (2014/05/06)
Catalytic-free coupling of aryl compounds and α-halo cycloketones via in situ generated oxyallyl cation intermediates is reported here. The reactions efficiently afford α-naphthol cycloalkanones with moderate to excellent yields. Electron-rich aromatic compounds are also used to produce the corresponding α-aryl cycloalkanones, and in some cases, analytically pure products are obtained after simple filtration followed by evaporation.
