157528-03-5

Basic information

• Product Name: 1-Bromo-6-(2'-ethynylphenyl)hex-5-yn-3-ol
• Synonyms: 1-Bromo-6-(2'-ethynylphenyl)hex-5-yn-3-ol
• CAS NO: 157528-03-5
• Molecular Weight: 277.161
• Mol File: 157528-03-5.mol

Chemical Properties

• CAS DataBase Reference: 1-Bromo-6-(2'-ethynylphenyl)hex-5-yn-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-6-(2'-ethynylphenyl)hex-5-yn-3-ol(157528-03-5)
• EPA Substance Registry System: 1-Bromo-6-(2'-ethynylphenyl)hex-5-yn-3-ol(157528-03-5)

Safety Data

• Hazardous Substances Data: 157528-03-5(Hazardous Substances Data)

Upstream product

• 120651-33-4 ((2‐ethynylphenyl)ethynyl)trimethylsilane 
• 157528-02-4 1-Bromo-6-<2'-<(trimethylsilyl)ethynyl>phenyl>hex-5-yn-3-ol 

Downstream Products

• 157528-04-6 1-Bromo-3-<(tert-butyldimethylsilyl)oxy>-6-(2'-ethynylphenyl)hex-5-yne 
• 157528-05-7 3-<(tert-Butyldimethylsilyl)oxy>-6-(2'-ethynylphenyl)-1-iodohex-5-yne 

Relevant articles and documents

Arene 1,4-Diradical Formation from o-Dialkynylarenes

A series of 10-membered cyclic 1,5-diynes has been prepared with arene rings fused at positions C-3/C-4.The arenes include simple benzene rings, a naphthoquinone and naphthohydroquinone, and an anthraquinone and anthracene unit.Consistent with a simple picture relating the extent of double bond character in the ene part of the ene-diyne with the rate of arene-1,4-diyl formation, the hydroquinone derivatives were much less reactive compared to the corresponding quinones.Substituents such as propargylic hydroxyl or keto group have a small but significant activating effect.The parent 3,4-benzo-1,8-decadiyne shows a half-life for rearrangement of 24 h at 84 deg C while the corresponding alkene, cyclodec-3-ene-1,5-diyne is reported to have a half-life of 18 h at 37 deg C.