1575402-41-3Relevant academic research and scientific papers
A bio-inspired synthesis of hybrid flavonoids from 2-hydroxychalcone driven by visible light
Gao, Yu-Qi,Hou, Yi,Zhu, Liming,Chen, Guzhou,Xu, Dongyang,Zhang, Sheng-Yong,He, Yupeng,Xie, Weiqing
, p. 29005 - 29009 (2019/09/30)
A bio-inspired synthesis of hybrid flavonoids from 2-hydroxylchalcone is described. Under the irradiation of 24 W CFL, 2-hydroxychalcone reacts with various nucleophiles to deliver structurally diverse hybrid flavonoids in good to excellent yields in the presence of a catalytic Br?nsted acid. Moreover, moderate enantioselectivities could be obtained using a catalytic chiral phosphoric acid via counter anion directed addition. Based on mechanistic studies, the reaction is proposed to proceed via tandem double-bond isomerization/dehydrated cyclization of 2-hydroxychalcone to form a transient flavylium cation, which is in situ captured by nucleophiles to afford hybrid flavonoids.
Extending the scope of oleic acid catalysis in diversity-oriented synthesis of chromene and pyrimidine based scaffolds
Ganesan, Asaithampi,Kothandapani, Jagatheeswaran,Subramaniapillai, Selva Ganesan
, p. 20582 - 20587 (2016/03/04)
Readily available, non-toxic, biodegradable oleic acid was found to catalyse 4H-chromene derivatives syntheses in good yields in a water medium. A facile domino one-pot protocol was also developed for the oleic acid catalysed pyrimidine-fused heterocycle
A facile synthesis of 2-aryl-4-(indol-3-yl)-4H-chromenes using amberlyst-15 as an efficient recyclable heterogeneous catalyst
Guha, Chayan,Sepay, Nayim,Mallik, Asok K.
, p. 1349 - 1354 (2015/02/19)
Starting from 2-hydroxychalcones and indoles, a facile synthesis of 2-aryl-4-(indol-3-yl)-4H-chromenes has been achieved by use of amberlyst-15, a sulfonated polystyrene resin, as a recyclable heterogeneous catalyst. The methodology involves a domino sequ
2-Methylindole as an indicative nucleophile for developing a three-component reaction of aldehyde with two different nucleophiles
Jiang, Dan,Pan, Xiaojuan,Li, Minghao,Gu, Yanlong
, p. 287 - 292 (2014/06/24)
2-Methylindole was used as an indicative nucleophile for rapid screening of MCRs of aldehydes with two different nucleophiles. By removal of some samples that have characteristic color associated with the generation of di(indolyl)methane derivatives the difficulties encountered in the product analysis were alleviated significantly.
