157557-32-9Relevant academic research and scientific papers
Non-innocence of 1,4-dicyanamidobenzene bridging ligands in dinuclear ruthenium complexes.
Choudhuri, Mohommad M. R.,Kaim, Wolfgang,Sarkar, Biprajit,Crutchley, Robert J.
, p. 11060 - 11066 (2013)
Four dinuclear complexes, [{RuII(ttpy)(bpy)}2(μ-L) ][PF6]2, where bpy is 2,2′-bipyridine, ttpy is 4-(tert-butylphenyl)-2,2′:6′,2″-terpyridine, and L is 2,5-dimethyl-, 2,5-dichloro-, 2,3,4,5-tetrachloro- and unsu
Near-infrared fluorescent ruthenium complex and application thereof in tumor photocatalytic drugs
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Paragraph 0046; 0053-0055, (2021/08/06)
The invention relates to the technical field of medicines, in particular to a near-infrared fluorescent ruthenium complex and application thereof in tumor photocatalytic drugs. The invention discloses a near-infrared fluorescent ruthenium complex, which has near-infrared fluorescence, has a relatively strong curative effect of photodynamic therapy on cervical cancer (HeLa cells) compared with the absorption peak red shift of most of the existing ruthenium complexes in a visible light region, has IC50 as low as 0.029 [mu]M under the condition of illumination, has a very strong growth inhibition capability on human cervical cancer cell strains, and has a photodynamic therapy index (PI) as high as 353.931. The complex can generate singlet oxygen under an illumination condition, and has a photocatalytic oxidation effect on NADH and NADPH at the same time. The complex has important significance for researching high-efficiency novel anti-tumor drugs, can be used for further preparing anti-tumor drugs, and has relatively high application value.
Use of metal complex compounds as catalysts for oxidation using molecular oxygen or air
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Page/Page column 18, (2010/02/15)
Use, as a catalyst for oxidation reactions using molecular oxygen and/or air, of at least one metal complex compound of formula (1) wherein Me is manganese, titanium, iron, cobalt, nickel or copper, X is a coordinating or bridging radical, n and m are each independently of the other an integer having a value of from 1 to 8, p is an integer having a value of from 0 to 32, z is the charge of the metal complex, Y is a counter-ion, q=z/(charge of Y), and L is a ligand of formula (2) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are each independently of the others hydrogen; unsubstituted or substituted C1-C18alkyl or aryl; cyano; halogen; nitro; —COOR12 or —SO3R12 wherein R12 is in each case hydrogen, a cation or unsubstituted or substituted C1-C18alkyl or aryl; —SR13, —SO2R13 or —OR13 wherein R13 is in each case hydrogen or unsubstituted or substituted C1-C18alkyl or aryl; —NR14R15; —(C1-C6alkylene)-NR14R15; —N(+)R14R15R16; —(C1-C6alkylene)-N(+)R14R15R16; —N(R13)—(C1-C6alkylene)-NR14R15; —N[(C1-C6alkylene)-NR14R15]2; —N(R13)—(C1-C6alkylene)-N(+)R14R15R16; —N[(C1-C6alkylene)-N(+)R14R15R16]2; —N(R13)—N—R14R15 or —N(R13)N″R14R15R16, wherein R13 is as defined above and R14, R15 and R16 are each independently of the other(s) hydrogen or unsubstituted or substituted C1-C18alkyl or aryl, or R14 and R15, together with the nitrogen atom linking them, form an unsubstituted or substituted 5-, 6- or 7-membered ring which may contain further hetero atoms. [in-line-formulae][LnMemXp]zYq??(1) [/in-line-formulae]
4-tert-butylphenyl solubilized oligopyridines
Constable, Edwin C.,Harverson, Peter,Smith, Diane R.,Whall, Louise A.
, p. 7799 - 7806 (2007/10/02)
Soluble 4-tert-butylphenyl substituted derivatives of 2,2':6',2''-terpyridine, 2,2':6',2'':6'',2'''-quaterpyridine, 2,2':6',2'':6'',2''':6''',2''''-quinquepyridine and 2,2':6',2'':6'',2''':6''',2'''':6'''',2'''''-sexipyridine have been prepared. The ligan
