1575816-39-5

Basic information

• Product Name: ethyl 3-amino-1-(2-bromophenyl)-1H-benzo[f]chromene-2-carboxylate
• Synonyms: ethyl 3-amino-1-(2-bromophenyl)-1H-benzo[f]chromene-2-carboxylate
• CAS NO: 1575816-39-5
• Molecular Weight: 424.294
• Mol File: 1575816-39-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 3-amino-1-(2-bromophenyl)-1H-benzo[f]chromene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-amino-1-(2-bromophenyl)-1H-benzo[f]chromene-2-carboxylate(1575816-39-5)
• EPA Substance Registry System: ethyl 3-amino-1-(2-bromophenyl)-1H-benzo[f]chromene-2-carboxylate(1575816-39-5)

Safety Data

• Hazardous Substances Data: 1575816-39-5(Hazardous Substances Data)

Upstream product

• 59803-32-6 ethyl 3-(2-bromophenyl)-2-cyanoacrylate 
• 135-19-3 β-naphthol 
• 105-56-6 ethyl 2-cyanoacetate 
• 6630-33-7 ortho-bromobenzaldehyde 

Relevant articles and documents

A simple green protocol for the synthesis of ethyl 3-amino-1-aryl-1H-benzo[f] chromene-2-carboxylates in aqueous media

An eco-friendly and efficient straightforward method has been developed for the synthesis of ethyl 3-amino-1-aryl-1H-benzo[f]chromene-2-carboxylate derivatives via 1,4-diazabicyclo[2.2.2]octane (DABCO)-catalysed cyclisation of β-naphthol and 3-aryl-2-cyanoacrylates using water as a green solvent. All products precipitated from the reaction mixture and were isolated by simple filtration. No further workup nor purification was necessary. The structure of ethyl 3-amino-1-aryl-1H-benzo[f]chromene-2-carboxylate was further confirmed by X-ray single crystal analysis.