157660-29-2Relevant academic research and scientific papers
Novel asymmetric desymmetrization of meso-1,2-diols via diastereoselective β-elimination of chiral α-arylsulfinyl acetals
Maezaki, Naoyoshi,Soejima, Motohiro,Takeda, Miwako,Sakamoto, Atsunobu,Matsumori, Yuki,Tanaka, Tetsuaki,Iwata, Chuzo
, p. 6527 - 6546 (2007/10/03)
Enantioselective desymmetrization of meso-1,2-diols was accomplished via diastereoselective C-O bond fission of acetals derived from various optically active β-ketosulfoxides with high diastereoselectivities. The substituent at the γ-position of the β-ketosulfoxide plays an important role in this cleavage.
A Novel Asymmetric Desymmetrisation of meso-Cyclopentane-1,2-diol via Diastereoselective β-Elimination of Chiral α-Arylsulfinyl Acetals
Maezaki, Naoyoshi,Soejima, Motohiro,Takeda, Miwako,Sakamoto, Atsunobu,Tanaka, Tetsuaki,Iwata, Chuzo
, p. 1345 - 1346 (2007/10/02)
meso-Cyclopentane-1,2-diol was differentiated via diastereoselective C-O bond fission of the acetal utilising the anion stabilised by a neighbouring chiral sulfinyl group to provide the chiral alcohol.
