1577229-08-3Relevant academic research and scientific papers
Efficient carbazole synthesis via Pd/Cu-cocatalyzed cross-coupling/ isomerization of 2-allyl-3-iodoindoles and terminal alkynes
Zhu, Can,Ma, Shengming
supporting information, p. 1542 - 1545 (2014/04/17)
The Pd/Cu-cocatalyzed one-pot reaction of 2-allyl-3-iodo-1-tosyl-1H-indoles and terminal alkynes afforded carbazoles highly efficiently via sequential carbon-carbon coupling, isomerization, cyclization, and aromatization forming a benzene ring. Both Pd and Cu are responsible for the coupling step, while K 2CO3 was observed to be critical for the subsequent cyclization.
