157729-46-9Relevant articles and documents
An easy access of 2',3'-dideoxy-3'-α-C-formyl-adenosine and -guanosine analogs via stereoselective C-C bond forming radical reaction
Sanghvi,Ross,Bharadwaj,Vasseur
, p. 4697 - 4700 (2007/10/02)
A large-scale, facile and stereoselective synthesis of 1-[5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-3-α-C-formyl-β-D-erythr o-pentofuranosyl] -adenine (7b) and -N2-isobutyrylguanine (7c) using an intermolecular radical C-C bond formation reaction is reported. The utility of these nucleosides (7b and 7c) as building blocks for antisense oligonucleosides is discussed.