157736-55-5

Usage

Uses

Used in Pharmaceutical Industry:
2-cyano-2-methylpropyl 4-methylbenzenesulfonate is used as a synthetic intermediate for the production of various pharmaceuticals. Its ability to undergo chemical reactions, such as nucleophilic substitution and reductive amination, allows for the creation of a wide range of drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
2-cyano-2-methylpropyl 4-methylbenzenesulfonate is also utilized as a synthetic intermediate in the agrochemical sector. Its versatility in chemical reactions enables the synthesis of various agrochemicals, including pesticides and herbicides, which are essential for crop protection and agricultural productivity.
Used in Chemical Reactions:
2-cyano-2-methylpropyl 4-methylbenzenesulfonate is used as a reactant in various chemical reactions due to its nitrile functional group. It can participate in nucleophilic substitution and reductive amination, among other reactions, making it a valuable component in the synthesis of different organic compounds for various industries.

Upstream product

• 19295-57-9 3-hydroxy-2,2-dimethylpropionitrile 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 19816-92-3 3,3-dimethyl azetidine 
• 79201-18-6 3,3-dimethyl-N-<4-methylphenylsulfonyl>azetidine 
• 1458654-16-4 3-(4-bromo-3,5-dimethylphenoxy)-2,2-dimethylpropanenitrile 

Relevant academic research and scientific papers

Pyrazolo[1, 5-a]pyridine compound, and preparation method and application thereof

The invention relates to a pyrazolo[1, 5-a]pyridine compound, a preparation method and application thereof, a pharmaceutical composition containing the compound as an active component, or a pharmaceutically acceptable salt of the compound. The invention further relates to application of the compound of formula (I) in the treatment and prophylaxis of diseases treatable with RET kinase inhibitors, including diseases or conditions mediated by RET kinases.

5-OXA-2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS

Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS

The present invention relates to compounds of general formula I, wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACID DERIVATIVES AND THEIR USE AS GPR40 RECEPTOR AGONISTS

The present invention relates to compounds of general formula I, (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

Benzamide derivatives and uses related thereto

Benzamide derivatives of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders:

A NOVEL SYNTHESIS OF 3,3-(SPIRO)SUBSTITUTED AZETIDINES

A smooth and efficient new synthesis for 3,3-disubstituted azetidines, starting from readily available nitriles, was estabilished: α-hydroxymethylation of the starting materials, followed by O-tosylation and LiAlH4-reduction of the key intermediates thus obtained, led - via spontaneous cyclization of the intermediate amino derivatives - to 3,3-disubstituted azetidines.Scope and limitations of this new method were studied with respect to generalized applicability: the target compounds were accessible in good yields for a variety of starting materials (cyclic and acyclic di(hetero)aryl, (hetero)arylalkyl, dialkyl, as well as basic moieties).The products thus obtained may be of interest for ensuing conversions due to their unblocked nitrogen.