15778-87-7

Upstream product

• 15778-83-3 2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 4602-73-7 3,4-dihydro-7-hydroxy-6-methoxy-isoquinoline 
• 40173-90-8 3,4-dimethoxyphenethyl bromide 
• 101038-22-6 1-(7-Benzyloxy-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-2-(3,4-dimethoxy-phenyl)-ethanone 
• 15357-95-6 7-(benzyloxy)-6-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 

Relevant academic research and scientific papers

8-PHENYL-ISOQUINOLINES AND PHARMACEUTICAL COMPOSITION THEREOF USED IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME

A series of 8-phenyl-isoquinoline derivatives (I) exhibit high binding affinity to 5-HT7 receptor (5-HT7R) and demonstrate potent antinociceptive activity in two animal models for Irritable Bowel Syndrome (IBS) by intraperitoneal injection (i.p.) or by oral administration (p.o.). These 5-HT7 receptor antagonists are a new class of therapeutic agents for the treatment of IBS.

8-Phenylisoquinolines And Pharmaceutical Composition Used In Treatment For Sepsis

A compound is provided. The compound includes a formula of: