157798-38-4Relevant academic research and scientific papers
Copper (II) complexes with tetradentate N4 and N2S2 ligands: effect of ligands on redox behavior and EPR parameters. Superoxide dismutase-like activity
Chautemps, Pierre,Gellon, Gisele,Morin, Benedicte,Pierre, Jean-Louis,Provent, Christophe,et al.
, p. 434 - 443 (2007/10/02)
Nine copper (II) complexes with tetradentate N4 and N2S2 (open chain or macrocyclic) ligands were prepared and studied in solution.For comparison, one N2O2 and one N3S ligand were included.EPR studies evidenced the stereochemistry around the copper (II) ion (square planar or tetrahedrally distorted).The redox or reduction potentials were obtained from electrochemical studies.UV-visible spectra gave additional information on the stereochemistry of the complexes and the deprotonation of amide ligands.The effect of ligands on redox behavior and stereochemistry is dicussed.Superoxide dismutase (SOD) activities were evidenced for the 11 complexes by spin-trapping method and by NBT assay.Unfortunately, the SOD activities do not survive bovine serum albumin in solution. - Keywords: Cu (II) complexes; EPR spectroscopy; electrochemistry; UV-visible spectroscopy; superoxide dismutase activity.
