157809-86-4

Basic information

• Product Name: 3-Isoquinolinecarboxamide,1-(2-chlorophenyl)-N-(1-methylpropyl)-, (S)- (9CI)
• CAS NO: 157809-86-4
• Molecular Formula: C₂₀H₁₉ClN₂O
• Molecular Weight: 338.83
• Mol File: 157809-86-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 597 °C at 760 mmHg
• Flash Point: 314.9 °C
• Density: 1.31 g/cm³
• Water Solubility: at 25 deg C (mg/L): 1.244
• CAS DataBase Reference: 3-Isoquinolinecarboxamide,1-(2-chlorophenyl)-N-(1-methylpropyl)-, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoquinolinecarboxamide,1-(2-chlorophenyl)-N-(1-methylpropyl)-, (S)- (9CI)(157809-86-4)
• EPA Substance Registry System: 3-Isoquinolinecarboxamide,1-(2-chlorophenyl)-N-(1-methylpropyl)-, (S)- (9CI)(157809-86-4)

Safety Data

• Hazardous Substances Data: 157809-86-4(Hazardous Substances Data)

Upstream product

• 419535-34-5 2-chloro-N-(2-hydroxy-1-methyl-2-phenylethyl)benzamide 
• 439614-60-5 1-(2-chlorophenyl)isoquinoline-3-carboxaldehyde 
• 89242-09-1 1-(2-chlorophenyl)-3-isoquinolinecarboxylic acid 
• 609-65-4 o-chlorobenzoyl chloride 
• 53631-70-2 d,l-norephedrine hydrochloride 
• 92853-34-4 1-(2-chlorophenyl)-3-methylisoquinoline 
• 33966-50-6 SEC-BUTYLAMINE 
• 109960-06-7 1-(2-chlorophenyl)-3-isoquinolinecarboxylic acid chloride 

Relevant articles and documents

A novel approach for the synthesis of the peripheral benzodiazepine receptor ligand, PK11195

A new synthesis of the peripheral benzodiazepine receptor ligand, PK11195 has been developed in only six-steps using a Heck-type reaction and a Suzuki coupling to effect the key transformations. The flexibility of this new approach is demonstrated by the

Novel irreversible ligands specific for 'peripheral' type benzodiazepine receptors: (±)-, (+)-, and (-)-1-(2-chlorophenyl)-N-(1 methylpropyl)-N-(2-isothiocyanatoethyl)-3-isoquinolinecarboxamide and 1-(2-isothiocyanatoethyl)-7-chloro-1,3-dihydro-5-(4-chlor

Novel ligands that bind irreversibly and selectively to 'peripheral' type benzodiazepine receptors (PBR) have been prepared. These compounds inhibits radiolabeled binding to PBR in the nanomolar range. The 2-isothiocyanatoethyl analogue of Ro 5-4864 (1-me