15783-56-9

Basic information

• Product Name: 2-chloro-4-(phenylamino)furo[3,4-d]pyrimidin-7(5H)-one
• Synonyms: 2-chloro-4-(phenylamino)furo[3,4-d]pyrimidin-7(5H)-one
• CAS NO: 15783-56-9
• Molecular Weight: 261.667
• Mol File: 15783-56-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-4-(phenylamino)furo[3,4-d]pyrimidin-7(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4-(phenylamino)furo[3,4-d]pyrimidin-7(5H)-one(15783-56-9)
• EPA Substance Registry System: 2-chloro-4-(phenylamino)furo[3,4-d]pyrimidin-7(5H)-one(15783-56-9)

Safety Data

• Hazardous Substances Data: 15783-56-9(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 15783-48-9 2,4-dichlorofuro[3,4-d]pyrimidin-7(5H)-one 
• 4156-75-6 furo<3,4-d>pyrimidine-2,4,7(1H,3H,5H)-trione 
• 142-04-1 aniline hydrochloride 

Downstream Products

• 15783-67-2 4-anilino-2-piperidin-1-yl-5H-furo[3,4-d]pyrimidin-7-one 

Relevant articles and documents

Probing the Reactivity of 2,4-Dichlorofuro[3,4-d ]pyrimidin-7-one: A Versatile and Underexploited Scaffold to Generate Substituted or Fused Pyrimidine Derivatives

Herein, we describe the results of our investigation on the chemical reactivity and versatility of a poorly explored scaffold: 2,4-dichlorofuro[3,4-d ]pyrimidin-7-one (3). Highly functionalized pyrimidines can be obtained with a divergent approach by reacting the key intermediate 3 with different amine nucleophiles under carefully controlled reaction conditions. The set-up of a microwave-Assisted one-pot, two-or three-step protocol to rapidly generate 2,4,5,6-Tetrasubstituted or fused pyrimidines is also reported.