157869-01-7Relevant academic research and scientific papers
A convenient synthesis of 4-chloro- and 4-bromocinnolines from o- aminophenylacetylenes
Vasilevsky,Tretyakov,Verkruijsse
, p. 1733 - 1736 (1994)
4-Chlorocinnolines and 4-bromocinnolines have been obtained in fair to good yields by diazotation of o-aminophenylacetylenes with sodium nitrite and concentrated hydrochloric acid or hydrobromic acid at temperatures between 25 and 30°C.
Cinnolines and Pyrazolopyridazines. - Novel Synthetic and Mechanistic Aspects of the Richter Reaction
Vasilevsky, Sergei F.,Tretyakov, Eugene V.
, p. 775 - 780 (2007/10/02)
The thermal cyclization of 2-alkynylbenzenediazonium salts 2 known as the Richter reaction and leading, as described in the literature, only to 4-hydroxycinnolines 6 has been studied.A new probable route to these compounds involving intermediate formation
