15789-02-3

Usage

Uses

Used in Chemical Synthesis:
N-BENZYL-3-HYDROXY-BENZAMIDE is used as a building block for the synthesis of various complex organic compounds. Its amide and alcohol functional groups allow for a wide range of chemical reactions, making it a versatile component in the creation of new molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, N-BENZYL-3-HYDROXY-BENZAMIDE is utilized as a starting material for the development of potential drug candidates. Its unique structure can be modified to create new compounds with specific therapeutic properties, contributing to the advancement of medicine.
Used in Drug Development:
N-BENZYL-3-HYDROXY-BENZAMIDE plays a crucial role in drug development, where its structure can be optimized to enhance the efficacy and safety of new pharmaceuticals. Its presence in a compound can influence pharmacokinetics, pharmacodynamics, and drug-target interactions, making it an essential component in the design of novel therapeutic agents.
Used in Organic Chemistry Studies:
As a benzamide derivative with both amide and alcohol functional groups, N-BENZYL-3-HYDROXY-BENZAMIDE is an important subject of study in organic chemistry. Researchers use it to explore reaction mechanisms, investigate the properties of functional groups, and develop new synthetic methods, furthering the understanding of organic chemistry principles.

InChI:InChI=1/C14H13NO2/c16-13-8-4-7-12(9-13)14(17)15-10-11-5-2-1-3-6-11/h1-9,16H,10H2,(H,15,17)

Upstream product

• 100-46-9 benzylamine 
• 16446-73-4 3-(chlorocarbonyl)phenyl acetate 
• 99-06-9 3-Carboxyphenol 
• 82082-48-2 N-benzyl-3-methoxybenzamide 
• 6304-89-8 3-acetoxybenzoic acid 
• 7781-98-8 ethyl-3-hydroxybenzoate 
• 19438-10-9 methyl 3-hydroxybenzoate 

Downstream Products

• 65261-33-8 N-Benzyl-3-phenoxybenzamid 
• 15505-00-7 4-(3-Benzylcarbamoyl-2,4,6-triiodo-phenoxy)-butyric acid 
• 15504-79-7 2-(3-Benzylcarbamoyl-2,4,6-triiodo-phenoxy)-butyric acid 
• 15504-67-3 N-Benzyl-3-hydroxy-2,4,6-triiodo-benzamide 
• 65261-60-1 N-Methyl-3-(3,4-dimethylphenoxy)-benzamid 

Relevant academic research and scientific papers

ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

The present invention relates to a compound suitable for use as a kinase inhibitor

QUINAZOLINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS

Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the modulation of the activity of, e.g., the inhibition of, one or more members of the TAM family kinases.

Microwave-assisted N-debenzylation of amides with triflic acid

A new and facile microwave-assisted protocol for the debenzylation of N-benzylamides with triflic acid has been developed. Both secondary and tertiary aliphatic or aromatic amides are obtained in moderate to good yields.

TEREPHTHALAMATE COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS HIV INTEGRASE INHIBITORS

Described herein are compounds having a terephthalamate structural feature. Also described herein, are methods of making such compounds, methods of using such compounds to modulate the activity of HIV integrase, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology of AIDS or infection with HIV.

Potential Central Nervous System Active Agents. 1. Synthesis of Aromatic N-Benzyl Amides

The preparation and spectral properties (IR, MS, NMR) are given for 18 aromatic N-benzyl amides, variously substituted on the acyl part, including four new ones and an (E)-cinnamide derivative.The amides were prepared by heating the appropriate N-benzylammonium salt in o-xylene, or from the reaction of the corresponding acid chloride with benzylamine.The occurrence of an intense peak in their mass spectra, which corresponds to the loss of the N-acyl substituent without hydrogen transfer, is reported.