157904-78-4

Basic information

• Product Name: <5R-(5α,6α)>-5,6,7,8-tetrahydro-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)naphtho<2,3-d><1,3>dioxole-6-carboxylic acid
• Synonyms: <5R-(5α,6α)>-5,6,7,8-tetrahydro-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)naphtho<2,3-d><1,3>dioxole-6-carboxylic acid
• CAS NO: 157904-78-4
• Molecular Weight: 412.396
• Mol File: 157904-78-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: <5R-(5α,6α)>-5,6,7,8-tetrahydro-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)naphtho<2,3-d><1,3>dioxole-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: <5R-(5α,6α)>-5,6,7,8-tetrahydro-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)naphtho<2,3-d><1,3>dioxole-6-carboxylic acid(157904-78-4)
• EPA Substance Registry System: <5R-(5α,6α)>-5,6,7,8-tetrahydro-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)naphtho<2,3-d><1,3>dioxole-6-carboxylic acid(157904-78-4)

Safety Data

• Hazardous Substances Data: 157904-78-4(Hazardous Substances Data)

Upstream product

• 55515-07-6 (1α,2α,3α)-podophyllotoxin 
• 518-28-5 podofilox 
• 477-48-5 podophyllotoxone 

Downstream Products

• 157831-14-6 methyl <5R-(5α,6α)>-5,6,7,8-tetrahydro-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)naphtho<2,3-d><1,3>dioxole-6-carboxylate 

Relevant articles and documents

A novel rearrangement product of podophyllotoxone - ester derivatives and in vitro cytotoxicity studies

A new rearrangement product of podophyllotoxone was obtained by reaction with strong bases. In vitro cytotoxicities of this substance and some derivatives were determined using L-1210 and KB cell lines.

The stereochemistry of thuriferic and epithuriferic acids

A new lignan, spithuriferic acid has been prepared from isopicropodophyllone. Its stereochemistry has been established on the basis of spectral, chemical and molecular modelling findings and compared to that of its 8' epimer thuriferic acid, isolated from the Juniperus thurifera leaves.