157916-18-2Relevant academic research and scientific papers
Synthesis of saframycins. IX. An efficient synthesis of the ABC ring of safracins
Saito, Naoki,Obara, Yasuko,Aihara, Tomoko,Harada, Shunji,Shida, Yukiko,Kubo, Arinori
, p. 3915 - 3928 (2007/10/02)
1,2,3,4,5,6-Hexahydro-10-hydroxy-1,5-imino-9-methoxy-3,8,11-trimethyl- 3-benzazocine 3b embodying all of the skeletal features of the ABC ring of safracins has been synthesized from compound 4a via a direct regioselective bromination, followed by the sequence reduction, metal-halogen interchange, and reaction of the organometallic intermediate with nitrobenzene. And the conversion of 3b to a quinone 21b is also described.
