157925-59-2Relevant academic research and scientific papers
Synthesis of 5-benzoyl-5-phenyl- and 5-phenylhydroxymethyl-5phenylhydantoins as potential anticonvulsants
Crooks,Deeks,DeSimone
, p. 1113 - 1117 (2007/10/02)
A series of 5-benzoyl-5-phenyl- and 5-phenyl-5-phenylhydroxymethylhydantoins have been synthesized from the reaction of urea, N-monosubstituted ureas and sym-N,N-disubstituted ureas with phenyltriketone hydrate, via a pinacol-pinacolone-type rearrangement mechanism. The compounds were evaluated for anti-convulsant activity in mice.
