1579293-00-7

Basic information

• Product Name: N-cyclohexyl-3-(4-fluorophenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydrocinnoline-4-carboxamide
• Synonyms: N-cyclohexyl-3-(4-fluorophenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydrocinnoline-4-carboxamide
• CAS NO: 1579293-00-7
• Molecular Weight: 397.493
• Mol File: 1579293-00-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-cyclohexyl-3-(4-fluorophenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydrocinnoline-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-3-(4-fluorophenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydrocinnoline-4-carboxamide(1579293-00-7)
• EPA Substance Registry System: N-cyclohexyl-3-(4-fluorophenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydrocinnoline-4-carboxamide(1579293-00-7)

Safety Data

• Hazardous Substances Data: 1579293-00-7(Hazardous Substances Data)

Upstream product

• 1579292-84-4 2-(cyclohexylamino)-3-(4-fluorobenzoyl)-6,6-dimethyl-6,7-dihydrobenzofuran-4(5H)-one 
• 931-53-3 Cyclohexyl isocyanide 
• 447-43-8 1-(4-fluorophenyl)-2,2-dihydroxyethan-1-one 
• 126-81-8 dimedone 

Relevant articles and documents

Efficient domino strategy for the synthesis of polyfunctionalized benzofuran-4(5 H)-ones and cinnoline-4-carboxamides

An efficient, three-component strategy for the improved synthesis of multifunctionalized 6,7-dihydrobenzofuran-4(5H)-ones under microwave irradiation in ethyl alcohol within short periods has been established. The synthesized benzofuran-4(5H)-ones have been readily converted into polyfunctionalized cinnoline-4-carboxamides by treating with hydrazine hydratein in the same solvent through a regioselective ring-opening of the furan. Tedious workup procedures can be avoided because of the direct precipitation of products from the reaction solution by water addition, thus rendering the two-steps process ecofriendly.