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• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 

Relevant academic research and scientific papers

The synthesis and strecker reaction of 2-chlorotetrafluoroethanesulfinyl ketimines

A series of 2-chlorotetrafluoroethanesulfinyl ketimines were prepared from 2-chlorotetrafluoroethanesulfinamide and ketones in high yields, and their Strecker reactions with TMSCN have been investigated. High yields and excellent diastereoselectivities were achieved in the presence of a catalytic amount of CsF under mild conditions. The six-membered chairlike models were proposed to account for the high stereoselective Strecker reaction.

One-pot asymmetric reductive amination of ketones induced by polyfluoroalkanesulfinamide

Using chiral 2-chloro-1,1,2,2-tetrafluoroethane-1-sulfinamide as the auxiliary, an efficient one-pot procedure for the asymmetric reductive amination of ketones was achieved in the presence of sodium borohydride. Both aromatic and aliphatic ketones reacte